(To the tune of “When Irish Eyes Are Smiling”) / Recording by David Simmons
The citric acid cycle
Is a source of energy
It gets electrons moving
While reducing NAD
It starts with citric acid
Turning to aconitate
Which becomes an isocitrate
On the way to glutarate
The loss of one more carbon
Gives succinyl-CoA
And then succinic acid
When the CoA goes away
A further oxidation
Gives one trans fumarate
Which gains a water on the
Next step to make malate
One simple oxidation
Makes O-A-A you see
Which combined with Ac-Co-A
Returns us cyclically

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