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Cell’s Lament

(To the tune of “Yesterday”) / Recording by Tim Karplus

Woe is me
My substrates are losing entropy
Causing gains in Gibbs free energy
Oh I can’t lose no en – tro- py

Re-a-lly
I could use a source of enthalpy
To combat the rise in Delta G
Oh I believe in enthalpy

I crave en-er-gy
Don’t you see?
It’s getting worse

My re-actions all
Soon will stall
And then rever-r-r-se

ATP
It’s the metabolic currency
Guess I’ll spend a bit judiciously
To help reduce the Delta G
Help reduce the Delta G

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