The Way They Work

(To the tune of “The Way We Were”) / Recording by Liz Bacon and David Simmons

Enzymes
Mighty powerhouse peptides
Cause reactions to go faster
In the cell’s insides

Tiny substrates
Bring about an induced fit
Enzyme structure is affect-ed
By what binds to it

Can it be that it’s just simple zen?
How the enzymes activate
If they bind effector, will they go
To an R-State, T-State?

Folding
Gives the mechanistic might
To three-D arrangement
Of the active site

*Enzymes
Have a bias they can’t hide
Hydrophobic side chains
Are mostly found inside

So it’s the structure
For celebrating
Whenever there’s debating
The way they work
The way they work

*An extra stanza compared to the original song